Author's Reply: Fecal Occult Blood Test

False Negative Fecal Occult Blood Test: Prozone Effect

Dear editor, the fecal occult blood test is the presently widely used screening laboratory test for colorectal cancer. At present, the test is usually based on an immunological diagnostic principle (1, 2). A false positive fecal occult blood is common and widely mentioned in literature. Nevertheless, the false negative is little mentioned in the paper. Here, the authors discuss the issue of the...

unochemical Fecal Occult Blood Test–Positive Individuals

Downlo kground: We aimed to define the potential of the fecal DNA assay as an alternative or in addition to rrently used immunochemical fecal occult blood test (iFOBT) for the early diagnosis of colorectal . thods: A total of 560 individuals aged 50 to 69 years with a positive iFOBT were recruited from an FOBT regional screening program. Twenty-six were diagnosed with adenocarcinoma, 264 with i...

NCD for Fecal Occult Blood Test

The Authors’ Reply

Fecal occult blood test screening for colorectal cancer.

In summary, high-quality scientific studies indicate that the use of the FOBT for colorectal cancer screening has a number of important advantages. The test is capable of detecting most early colorectal cancers and many advanced adenomas. It has been shown in randomized, controlled trials to reduce substantially colorectal cancer mortality and incidence. The FOBT is feasible, widely available, ...